Megaloblastic anaemia in coeliac disease treated with folic acid.
نویسندگان
چکیده
منابع مشابه
Folic Acid in Coeliac Disease
Folic acid, as a component of the vitamin B complex, has ben recognized for many years as an estial food factor. Crude preparations of it we shown to have a haernopoietic effect in some animals. Deficiency of it was followed by depression of the formation of red cells, white cells, and platelets. In 1945 Angier et aL (1945) synthesized pure folic acid. Spies (1945) and his co-workers were the f...
متن کاملFolic Acid in Coeliac Disease a Study of Its Admniistration in Twenty-two Cases
Folic acid, as a component of the vitamin B complex, has ben recognized for many years as an estial food factor. Crude preparations of it we shown to have a haernopoietic effect in some animals. Deficiency of it was followed by depression of the formation of red cells, white cells, and platelets. In 1945 Angier et aL (1945) synthesized pure folic acid. Spies (1945) and his co-workers were the f...
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Only two (2.5%) of 80 outpatients with histologically proven ulcerative colitis had folate deficiency associated with anaemia or macrocytosis. Mean folate absorption, measured using micrograms/kg body weight of a tritium-labelled physiological folate derivative, 5-methyltetrahydroteroylglutamic acid, in six newly diagnosed patients was 76.7% (normal greater than 95%) but fell to 69.4% after thr...
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A 60 year old man with ulcerative colitis since 1975 and treated with sulphasalazine, presented with severe megaloblastic anaemia caused by folate deficiency. The drug was stopped, and the anaemia recovered promptly. There was no relapse one year later.
متن کاملUrinary formiminoglutamic acid in the megaloblastic anaemias associated with pregnancy and malnutrition.
The pathogenesis of many of the common forms of megaloblastic anaemia in malnourished populations is obscure. The aetiological factors and response to therapy vary in different geographical areas, and confusion has arisen by the retention of certain ambiguous terms. Thus "nutritional megaloblastic anaemia" is often really megaloblastic anaemia associated with pregnancy, and "tropical megaloblas...
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عنوان ژورنال:
- Lancet
دوره 2 6571 شماره
صفحات -
تاریخ انتشار 1949